Lung cancer is the leading cause of cancer-related death for both men and women in the U.S., according to the American Cancer Society (ACS). Responsible for 1 in 4 cancer deaths, there were approximately 224,390 new cases and 158,000 lung cancer deaths in 2016 alone.
Despite the seemingly grim outlook for lung cancer patients, many people diagnosed with the disease are cured. The key for these positive outcomes is early cancer detection and treatment. A number of new and innovative therapies have been developed that have contributed greatly to the prolonged survival of patients. However, as the statistics show, there is still a vital need for better treatment options to further improve survival rates.
A main focus in cancer research has been to target the cell communication that causes normal cells to change into cancerous cells. Our understanding of these processes has grown significantly during the past decade, and scientists have been able to point to a number of proteins that are involved in this transformation. Recently, a group of scientists combined its knowledge of these cellular processes with a high-tech anti-cancer drug delivery method to wipe out lung cancer cells. They used nanoparticles with a drug that specifically targeted a protein known to be involved in this cell-changing process. Nanoparticles are very tiny particles between 1 and 100 nanometers—about 1,000 times smaller than a cell—that are made of special material depending on their use. Here, they used a special type of nanoparticle that allowed the drug to get into the lung cancer cells.
In addition to new therapies to fight cancer, there are low-tech ways you can reduce your cancer risk. One of the main causes of lung cancer is smoking tobacco products. The No. 1 way to stay healthy is to avoid tobacco, including smokeless tobacco products, which can also cause cancer. Tomorrow, November 17, is the Great American Smokeout—a good day to make a commitment to quit. ACS has a number of stop-smoking resources available on its website. Additionally, eating healthy and staying active will reduce your risk for cancer-related illness.
Audrey A. Vasauskas, PhD, is an associate professor of physiology at the Alabama College of Osteopathic Medicine. She is a former volunteer editor for the I Spy Physiology blog.