How Your Liver Handles Fat Is a Fine Balancing Act

Image created with Biorender. Credit: Rory Cunningham Keeping a healthy amount of fat in your liver is simple on paper, but a little more complicated when you look under the metabolic hood. Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver injury that can range progressively from fat accumulation inside liver cells (steatosis), to … Continue reading How Your Liver Handles Fat Is a Fine Balancing Act

2022’s Most-read I Spy Physiology Posts

Credit: iStock This year, as COVID-19 vaccines and boosters protected most of us from severe disease, scientists and educators returned to labs, classrooms and in-person meetings with a lot of new physiology research to share. In 2022, our member-contributors wrote about the physiology of space travel, new techniques to improve organ transplantation and why exercise … Continue reading 2022’s Most-read I Spy Physiology Posts

How Technology and Physiology Are Making Sick Livers Transplantable

Credit: iStock Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver disease that begins with excess fat accumulation in liver cells. Left unchecked, this can progress to a more advanced disease stage, called nonalcoholic steatohepatitis (NASH), that involves scarring and inflammation of the liver. There aren’t any approved therapies for NASH yet, which means … Continue reading How Technology and Physiology Are Making Sick Livers Transplantable

Why Liver Cells Are Like a Rowing Crew

Credit: iStock At the back of a rowing boat sits the coxswain (pronounced “kaak-sn”) or “cox” for short. Unlike the rest of the muscle-bound rowing crew, the cox is much smaller and does not actually row. You might wonder: Why they should be kept in the boat if they don’t help with the energy-demanding tasks? … Continue reading Why Liver Cells Are Like a Rowing Crew